Regensburg Pediatric Appendicitis
This repository holds the data from a cohort of pediatric patients with suspected appendicitis admitted with abdominal pain to Children’s Hospital St. Hedwig in Regensburg, Germany, between 2016 and 2021. Each patient has (potentially multiple) ultrasound (US) images, aka views, tabular data comprising laboratory, physical examination, scoring results and ultrasonographic findings extracted manually by the experts, and three target variables, namely, diagnosis, management and severity.
Characteristics
Subject Area
Associated Tasks
Attribute Type
# Instances
# Attributes
Info
This dataset was acquired in a retrospective study from a cohort of pediatric patients admitted with abdominal pain to Children’s Hospital St. Hedwig in Regensburg, Germany. Multiple abdominal B-mode ultrasound images were acquired for most patients, with the number of views varying from 1 to 15. The images depict various regions of interest, such as the abdomen’s right lower quadrant, appendix, intestines, lymph nodes and reproductive organs. Alongside multiple US images for each subject, the dataset includes information encompassing laboratory tests, physical examination results, clinical scores, such as Alvarado and pediatric appendicitis scores, and expert-produced ultrasonographic findings. Lastly, the subjects were labeled w.r.t. three target variables: diagnosis (appendicitis vs. no appendicitis), management (surgical vs. conservative) and severity (complicated vs. uncomplicated or no appendicitis). The study was approved by the Ethics Committee of the University of Regensburg (no. 18-1063-101, 18-1063_1-101 and 18-1063_2-101) and was performed following applicable guidelines and regulations.
Introductory Paper
By Ricards Marcinkevics, Patricia Reis Wolfertstetter, Ugne Klimiene, Ece Ozkan, Kieran Chin-Cheong, Alyssia Paschke, Julia Zerres, Markus Denzinger, David Niederberger, S. Wellmann, C. Knorr, Julia E. Vogt. 2023
Provided by
University of California, Irvine
Creators
- Ricards Marcinkevics
- Patricia Reis
- Ugne Klimiene
- Ece Ozkan
- Kieran Chin-Cheong
- Alyssia Paschke
- Julia Zerres
- Markus Denzinger
- David Niederberger
- S. Wellmann
- C. Knorr
- Julia E.
DOI
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Features
| Attribute Name | Role | Type | Demographic | Description | Units | Missing Values |
|---|---|---|---|---|---|---|
| Age | Feature | Continuous | Age | Obtained from the date of birth | years | yes |
| BMI | Feature | Continuous | Measures body fat; patient's weight divided by the square of the height | yes | ||
| Sex | Feature | Categorical | Sex | Registered gender | yes | |
| Height | Feature | Continuous | Patient's height | yes | ||
| Weight | Feature | Integer | Patient's weight | yes | ||
| Length_of_Stay | Feature | Integer | Length of the stay in the hospital | yes | ||
| Management | Target | Categorical | (conservative, primary surgical, secondary surgical, simultaneous appendectomy) Management of the patient assigned by a senior pediatric surgeon: operative (appendectomy: laparoscopic, open or conversion) or conservative (without antibiotics). In case of the secondary surgery after prior stay, the patient was labelled as operatively managed. | yes | ||
| Severity | Target | Categorical | (uncomplicated, complicated) Severity of appendicitis: uncomplicated: subacute/ catharral, fibrosis; phlegmonous or complicated: gangrenous, perforated, abscessed | yes | ||
| Diagnosis_Presumptive | Other | Binary | Patient's suspected diagnosis | yes | ||
| Diagnosis | Target | Binary | Patient's diagnosis, histologically confirmed for operated patients. Conservatively managed patients were labelled as having appendicitis if they had an AS or PAS of ≥ 4 and an appendix diameter of ≥ 6 mm | yes | ||
| Alvarado_Score | Feature | Integer | Patient's score according to the scoring system | yes | ||
| Paedriatic_Appendicitis_Score | Feature | Integer | Patient's score according to the scoring system | yes | ||
| Appendix_on_US | Feature | Binary | Detectability of the vermiform appendix during sonographic examination | yes | ||
| Appendix_Diameter | Feature | Integer | Maximal outer diameter of the appendix | yes | ||
| Migratory_Pain | Feature | Binary | Abdominal pain; usually starts in epigastrium and moves to the right lower quadrant | yes | ||
| Lower_Right_Abd_Pain | Feature | Binary | Right iliac fossa pain detected on palpation | yes | ||
| Contralateral_Rebound_Tenderness | Feature | Binary | A state in which pain of the contralateral side (usually, the right lower quadrant) is felt on the release of pressure (usually, in the left lower quadrant) over the abdomen | yes | ||
| Coughing_Pain | Feature | Binary | Abdominal pain by forced cough | yes | ||
| Nausea | Feature | Binary | Feeling of sickness/ejection of contents from stomach through the mouth | yes | ||
| Loss_of_Appetite | Feature | Binary | yes | |||
| Body_Temperature | Feature | Continuous | Measured by a thermometer placed in the rectum or in the auditory canal | yes | ||
| WBC_Count | Feature | Continuous | The number of leucocytes in a unit volume of blood; inflammation parameter | yes | ||
| Neutrophil_Percentage | Feature | Integer | Mature WBC in the granulocytic series | yes | ||
| Segmented_Neutrophils | Feature | Integer | Most mature neutrophilic granulocytes present in circulating blood, increased during an inflammatory disorder | yes | ||
| Neutrophilia | Feature | Categorical | Relative neutrophilic leucocytosis, often a result of a bacterial infection | yes | ||
| RBC_Count | Feature | Continuous | The number of erythrocytes in a unit volume of blood | yes | ||
| Hemoglobin | Feature | Continuous | Hemoglobin level; a red protein in the red blood cells that contains iron and is responsible for transporting oxygen | yes | ||
| RDW | Feature | Continuous | A blood test that measures the differences in the volume and size of the erythrocytes | yes | ||
| Thrombocyte_Count | Feature | Integer | The number of platelets in a unit volume of blood | yes | ||
| Ketones_in_Urine | Feature | Categorical | Presence of ketone bodies in urine, e.g. in case of anorexia | yes | ||
| RBC_in_Urine | Feature | Categorical | Blood in urine | yes | ||
| WBC_in_Urine | Feature | Categorical | Leucocytes in urine, e.g., in case of infection | yes | ||
| CRP | Feature | Integer | Protein produced by the liver, elevated in case of inflammation, infection, or injury | yes | ||
| Dysuria | Feature | Binary | Pain or other difficulty during urination | yes | ||
| Stool | Feature | Categorical | Characteristics of bowel movements | yes | ||
| Peritonitis | Feature | Categorical | Spasm of abdominal wall muscles detected on palpation, usually a result of inflammation | yes | ||
| Psoas_Sign | Feature | Categorical | Abdominal pain produced by extension of the hip | yes | ||
| Ipsilateral_Rebound_Tenderness | Feature | Categorical | A state in which pain of the ipsilateral side is felt on the release of pressure over the abdomen | yes | ||
| US_Performed | Feature | Categorical | If an abdominal ultrasonography was performed or not | yes | ||
| US_Number | Feature | Integer | yes | |||
| Free_Fluids | Feature | Categorical | Free fluids inside the abdomen | yes | ||
| Appendix_Wall_Layers | Feature | Categorical | Distribution and characteristics of appendix layers, e.g., irregular in case of an increasing inflammation | yes | ||
| Target_Sign | Feature | Categorical | Axial image of appendix with a fluid-filled center surrounded by echogenic mucosa and submucosa and hypoechoic muscularis | yes | ||
| Appendicolith | Feature | Categorical | Presence of fecalith in the appendix, e.g. acoustic shadow | yes | ||
| Perfusion | Feature | Categorical | Blood flow to the appendix wall | yes | ||
| Perforation | Feature | Categorical | Signs of appendix perforation in US | yes | ||
| Surrounding_Tissue_Reaction | Feature | Categorical | Inflammation signs in tissue (i.a. in omentum/fat tissue) surrounding appendix | yes | ||
| Appendicular_Abscess | Feature | Categorical | Appendiceal mass | yes | ||
| Abscess_Location | Feature | Categorical | Location of the abcess intraperitoneal | yes | ||
| Pathological_Lymph_Nodes | Feature | Binary | Enlarged and inflamed intra-abdominal lymph nodes | yes | ||
| Lymph_Nodes_Location | Feature | Categorical | The location of pathological lymph nodes in the abdomen | yes | ||
| Bowel_Wall_Thickening | Feature | Binary | Edema of the intestinal wall, > 2-3 mm for small bowel wall thickening | yes | ||
| Conglomerate_of_Bowel_Loops | Feature | Binary | Small intestine conglomerate as sign of intraperitoneal inflammation | yes | ||
| Ileus | Feature | Categorical | Sonographic signs of paralytic ileus (e.g., dilated intestinal loops, pendulum peristalsis or absence of peristalsis) | yes | ||
| Coprostasis | Feature | Categorical | Fecal impaction in the colon | yes | ||
| Meteorism | Feature | Categorical | Accumulation of gas in the intestine | yes | ||
| Enteritis | Feature | Categorical | Sonographic features of gastroenteritis, e.g. wall thickening of ileum, increased peristalsis | yes | ||
| Gynecological_Findings | Feature | Categorical | Gynaecological abnormalities, e.g. cysts, ovarial torsion | yes |